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ABO blood group system is of significant identified by Karl Landsteiner. ABO typing involves both antigen typing and antibody detection. Gene for allele-I is present which determines blood group type. Further, differentiation of blood group takes place by Rh factor. Blood group type also effect on person interests toward different things including games. 180 students took part in study that how blood group type effect on trend toward games and results were different for each blood group.