Innovative Journal of Medical Sciences <div id="myCarousel" data-ride="carousel"> <div> <div style="text-align: justify;"><strong>Innovative Journal of Medical Sciences</strong><strong> (IJMS) </strong>is an international Referred and Peer Reviewed Online Journal with E-ISSN: 2581-4346 published by B.R. Nahata Smriti Sansthan for the enhancement of Medical Sciences subject areas. The journal’s full text is available online at <a href=""></a> . The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles. The Journal has been designed to cover all the fields of research, which has any correlation and impact on Pharmaceutical and medical science. IJMS aims for a quick publication of research articles post review by the Editorial Board. <strong>IJMS free submission provides platform for the new researchers to get there researches published with rapid review.</strong> The members of the Editorial Board of IJMS are of international stature coming across the globe, many of whom are well known eminent academicians and researchers which allows the complete coverage of the scope of the journal. IJMS accepts new technologies, or research or research methods with applicability to pharmacy practice in fields such as pharmaceutical care, medication therapy management, Pharmaceutical Technology, Pharmacognosy, Natural Product Research, Pharmaceutics, Novel Drug Delivery, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest , Medical science ,APHE , Organ system, psychosocial aspects of medication use, pharmacoeconomics, pharmacotherapy, pharmacoepidemiology, pharmacy law, pharmacy management, public health, and health care financing.</div> </div> </div> <div style="text-align: justify;"> <p style="text-align: justify;"> </p> <p style="text-align: justify;"><strong><span style="text-decoration: underline;">SUBJECT CATEGORY </span></strong></p> <p style="text-align: justify;"><strong>Papers reporting original research and innovative applications from all parts of the world are welcome.</strong></p> <p style="text-align: justify;"><strong>Subject areas suitable for publication include, but are not limited to the following fields:</strong></p> <ul style="text-align: justify;"> <li>Pharmaceutical care,</li> <li>Medication therapy management,</li> <li>Pharmaceutical technology,</li> <li>Pharmacognosy,</li> <li>Natural product research,</li> <li>Pharmaceutics,</li> <li>Novel drug delivery,</li> <li>Biopharmaceutics,</li> <li>Pharmacokinetics,</li> <li>Pharmaceutical/medicinal chemistry,</li> <li>Computational chemistry and molecular drug design,</li> <li>Pharmacology,</li> <li>Pharmaceutical analysis,</li> <li>Pharmacy practice,</li> <li>Clinical and hospital pharmacy,</li> <li>Cell biology,</li> <li>Genomics and proteomics,</li> <li>Pharmacogenomics,</li> <li>Bioinformatics and biotechnology of pharmaceutical interest,</li> <li>Medical science,</li> <li>APHE</li> <li>Organ system,</li> <li>Psychosocial aspects of medication use,</li> <li>Pharmacoeconomics,</li> <li>Pharmacotherapy,</li> <li>Pharmacoepidemiology,</li> <li>Pharmacy law,</li> <li>Pharmacy management,</li> <li>Public health and health care financing.</li> <li>Anatomical pathology</li> <li>Cytology</li> <li>Immunology</li> <li>Clinical biochemistry</li> <li>Microbiology</li> <li>Blood transfusion</li> <li>Haematology</li> <li>Virology</li> <li>Genetics and Molecular pathology</li> <li>Cardiology (Heart Care)</li> <li>Oncology (Cancer Care)</li> <li>Neurology</li> <li>Urology</li> <li>Surgical Gastroenterology</li> <li>Medical Gastroenterology</li> <li>Obstetrics and Gynecology</li> <li>Bone Marrow Transplant</li> <li>Orthopedics &amp; Joint Replacement</li> <li>Pulmonology (Lung Diseases)</li> <li>Bariatric/Weight Loss Surgery</li> <li>Robotic Surgery</li> <li>Liver Transplant</li> <li>Kidney Transplant</li> <li>Reproductive Medicine (IVF)</li> <li>Aerospace Medicine</li> <li>Anesthesia</li> <li>Bariatric Surgery</li> <li>Cardiology - Interventional</li> <li>Cardiology - Non Interventional</li> <li>Cardiothoracic And Vascular Surgery</li> <li>Centre For Spinal Diseases</li> <li>Clinical Haematology And BMT</li> <li>Corneal Transplant</li> <li>Critical Care Medicine</li> <li>Dermatology And Cosmetology</li> <li>Ear Nose Throat Head And Neck Surgery</li> <li>Emergency Medicine</li> <li>Endocrinology</li> <li>General Surgery</li> <li>Infectious Diseases</li> <li>Internal Medicine</li> <li>In-Vitro Fertilization (IVF)</li> <li>Laboratory Medicine</li> <li>Liver Transplant &amp; Hepatic Surgery</li> <li>Maxillofacial Surgery</li> <li>Medical Gastroenterology</li> <li>Medical Oncology &amp; Clinical Hematology</li> <li>Medical Oncology</li> <li>Minimally Invasive Gynecology</li> <li>Neonatology</li> <li>Nephrology</li> <li>Neuro Modulation</li> <li>Nutrition &amp; Dietetics</li> <li>Neurology</li> <li>Neurosurgery</li> <li>Obstetrics And Gynecology</li> <li>Ophthalmology</li> <li>Orthopedics &amp; Joint Replacement</li> <li>Pain Management</li> <li>Pediatric Surgery</li> <li>Physiotherapy</li> <li>Plastic Surgery</li> <li>Psychiatry</li> <li>Pulmonology</li> <li>Renal Transplant</li> <li>Reproductive Medicine &amp; IVF</li> <li>Rheumatology</li> <li>Robotic Surgery</li> <li>Surgical Gastroenterology</li> <li>Surgical Oncology</li> <li>Urology</li> <li>Vascular and endovascular surgery</li> </ul> <p style="text-align: justify;"> </p> <p style="text-align: justify;"><strong><span style="text-decoration: underline;">JOURNAL PARTICULARS</span></strong></p> <table> <tbody> <tr> <td width="281"> <p>Title</p> </td> <td width="517"> <p><strong>Innovative Journal of Medical Sciences</strong></p> </td> </tr> <tr> <td width="281"> <p>Frequency</p> </td> <td width="517"> <p>Quarterly</p> </td> </tr> <tr> <td width="281"> <p>E- ISSN</p> </td> <td width="517"> <p>2581-4346</p> </td> </tr> <tr> <td width="281"> <p>P-ISSN</p> </td> <td width="517"> <p>-</p> </td> </tr> <tr> <td width="281"> <p>DOI</p> </td> <td width="517"> <p><strong><a href=""></a></strong></p> </td> </tr> <tr> <td width="281"> <p>Publisher</p> </td> <td width="517"> <p><strong>Mr. Rahul Nahata</strong>, B.R. Nahata College of Pharmacy, Mhow-Neemuch Road, Mandsaur-458001, Madhya Pradesh</p> </td> </tr> <tr> <td width="281"> <p>Chief Editor</p> </td> <td width="517"> <p>Dr. M.A. Naidu</p> </td> </tr> <tr> <td width="281"> <p>Starting Year</p> </td> <td width="517"> <p>2017</p> </td> </tr> <tr> <td width="281"> <p>Subject</p> </td> <td width="517"> <p>Computer Science and Engineering subjects</p> </td> </tr> <tr> <td width="281"> <p>Language</p> </td> <td width="517"> <p>English Language</p> </td> </tr> <tr> <td width="281"> <p>Publication Format</p> </td> <td width="517"> <p>Online</p> </td> </tr> <tr> <td width="281"> <p>Email Id</p> </td> <td width="517"> <p>[email protected],[email protected]</p> </td> </tr> <tr> <td width="281"> <p>Mobile No.</p> </td> <td width="517"> <p>+91-7049737901</p> </td> </tr> <tr> <td width="281"> <p>Website</p> </td> <td width="517"> <p><a href="" aria-invalid="true"></a></p> </td> </tr> <tr> <td width="281"> <p>Address</p> </td> <td width="517"> <p>B.R. Nahata Smriti Sansthan, BRNSS PUBLICATION HUB, B.R. Nahata College of Pharmacy, Mhow-Neemuch Road, Mandsaur-458001, Madhya Pradesh</p> </td> </tr> </tbody> </table> <p style="text-align: justify;"> </p> </div> en-US <p>This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.</p> [email protected] (Prof. M A Naidu) [email protected] (Dr. Nilesh Jain) Fri, 12 Jul 2024 05:42:31 +0000 OJS 60 Enhancing patient safety: Materiovigilance and medical device surveillance in India and global perspectives <p>The post-marketing vigilance system for medical devices in India is not as robust as that for drugs. Materiovigilance, which focuses on monitoring and reporting adverse events associated with medical devices, is an essential aspect of post-marketing surveillance. Various countries, including India, have implemented their own post-marketing surveillance systems in accordance with the World Health Organization’s directives. In India, this system is known as the materiovigilance program of India (MvPI). This article aims to evaluate the current status of MvPI, compare it with the systems in developed countries, and propose specific measures to enhance the effectiveness of the program.</p> N. Javali Ratna Copyright (c) 2024 N. Javali Ratna Wed, 15 Mar 2023 00:00:00 +0000 William Mackenzie blighted ovum syndrome: An educational ultrasound image and review <p>Background: A blighted ovum syndrome occurs when a pregnant female had anembryonic gestation with normal gestational sac but without an embryo. The embryo may have not developed or it developed but has reabsorbed. William Mackenzie was most probably the first to provide a detailed account of the condition which included a description of a blighted ovum dissection. Since the 1970s, blighted ovum syndrome has been increasingly recognized as a cause of recurrent miscarriages. The aim of this paper is to provide and educational ultrasound image and an educational review. Patients and Methods: The case of a 39-year-old female who experienced a blighted ovum syndrome is described. Results: A 39-year-old primigravida female was tested positive for pregnancy, and within few days, she experienced spotting of blood. Ultrasound examination showed anteverted gravid uterus with a single gestational with yolk sac without fetal pole. The mean gestational sac diameter was at six weeks. Both adnexa were normal and the cervix was closed. Four days later, the patient experienced pain and bleeding indicating miscarriage. Conclusion: This paper emphasizes the vital role of ultrasound examination in the timely and confident diagnosis of blighted ovum syndrome.</p> Aamir Jalal Al Mosawi Copyright (c) 2024 Aamir Jalal Al Mosawi Wed, 15 Mar 2023 00:00:00 +0000 Exploration and prevalence of atopic dermatitis in adults <p>Human skin is the largest organ and therefore, it has the most chance to get affected at first, and it becomes important to go in-depth to check the dermatologic condition that can be done under the study of dermatology. There are various dermatologic conditions from mild to worst leading to skin cancer as well. This article covers the basic dermatologic conditions known as atopic dermatitis and a detailed overview on it, like what it is, what are its types, how it is diagnosis, and how it is treated. A research survey is conducted between the students from different cities and of different ages. The aim of this study is to know about the factor on which atopic dermatitis mainly attacks. Results claim that there must be some environmental conditions and genetic factors responsible for the prevalence of this disease.</p> Afra Malik Copyright (c) 2024 Afra Malik Wed, 15 Mar 2023 00:00:00 +0000 Computational approaches highlighting conotoxins as potential drug against breast and pancreatic cancer treatment <p>Introduction: The two most common cancer-related causes of mortality, breast and pancreatic cancer, account for a significant portion of deaths worldwide. Our research included genomic and docking investigations using a variety of cancer illness datasets, for the identification of potential hub genes as target receptors. Based on literature reviews, we focused on conotoxins, a marine animal-derived substance secreted by cone snails, which serves as a ligand protein in the treatment of many disorders like cancer. Methods: The Gene Expression Omnibus (GEO) dataset of NCBI was used to compile the information on breast and pancreatic cancer. In this study, two microarray datasets (GSE36775 and GSE113865) were evaluated and screened out significantly differentially expressed genes (DEGs) that had P&lt;0.05, using NCBI GEO2R. Furthermore, Cytoscape is used to examine the highly conserved genes across various cancer types. A protein-protein docking study was conducted using the H-Dock server. Results: Gene conservancy studies revealed that 963 genes in total were preserved in two significant cases. To identify their metabolic pathways, a system biology approach was used, and docking studies of receptor proteins against diverse conotoxins were also conducted. The two compounds with the highest docking scores are CCNB1 + conotoxinPVIIA (-257.64 Kcal/mol) and CDK1 + conotoxinGeXIVA (-246.66 Kcal/mol), respectively. Conclusion: In the fight against cancer, our study has shown that conotoxins-derived peptides have enormous promise for selectively targeting cancer cells. We concluded that animal-based compounds may unveil new areas of study for researchers.</p> Mukesh Nitin Copyright (c) 2024 Mukesh Nitin Wed, 15 Mar 2023 00:00:00 +0000 The use of orlistat in diabetes: An educational article and expert opinion <p>In 1998, Hermann Toplak and Marhardt reported the emergence and registration of orlistat in Austria. Orlistat is an intestinal lipase inhibitor which decreases intestinal triglycerides absorption and helps in lowering the ultimate calorie intake. The aim of this paper is to provide an overview of orlistat research progress in diabetes. There has been accumulating convincing evidence suggesting that the use of orlistat in type 2 diabetes can have beneficial effects on diabetic control, body weight, glycosylated hemoglobin (HbA1C), and insulin resistance.</p> Aamir Jalal Al Mosawi Copyright (c) 2024 Aamir Jalal Al Mosawi Wed, 15 Mar 2023 00:00:00 +0000